Our Lady of Perpetual Help Parish was established in 1942. The first church was a wing of Holy Trinity Church which was moved to 7617 Cortland in the Love Field area to serve until a new church could be built. Father S. E. Bryne was the first pastor.
The parish hall, built in the summer of 1946, served as the parish school until the present school was finished in 1950. Sisters of Charity of the Incarnate Word staffed the school. Their convent was built in 1947.
In February 1954, the parish was divided when St. Monica Parish was established and Bishop Danglmayr became pastor of the new parish. Father Clair E. McTamney became the new pastor; he was succeeded by Father Lawrence M. DeFalco who remained at OLPH until March 1963.
When the church was destroyed by fire in January 1963, Father Fred Mosman was pastor. Father Mosman initiated plans for the new church, but before construction began, he was assigned as first pastor of the St. Patrick Parish.
The new church, a brick structure, was dedicated in April 1964. It consists of natural stained-wood ceilings, asphalt flooring and stained-glass windows. The seating capacity is 300.
Highlighting the interior of the church is a mosaic mural which forms a reredos behind the altar. The mural was designed and executed by Joaquin Medrano and is a copy of an original picture which hangs in the Church of St. Alphonsus in Rome.
In the upper portion of the mural, a copy of the original picture of Our Lady of Perpetual Help done in mosaic shows Our Lady and her divine Son in heaven. The symbol for God the Father is above her head. Beneath the picture, the Holy Spirt in the form of a dove hovers above the Crucifix.